Author Question: The nurse wants to discuss the biotransformation reaction to a student. What is the best explanation ... (Read 33 times)

karateprodigy · **on:** Jul 24, 2018

The nurse wants to discuss the biotransformation reaction to a student. What is the best explanation by the nurse?

1. Biotransformation converts drugs from one form to another that can result in increased or decreased activity.
2. Biotransformation is the final step in excretion of a drug from the body.
3. Biotransformation does not change the effect of a drug.
4. Biotransformation is the process of absorption.

Question 2

A nurse is conducting an inservice for students regarding drug excretion. Which responses by the students indicate an understanding of drug excretion? (Select all that apply.)

Note: Credit will be given only if all correct choices and no incorrect choices are selected.

1. Breast milk
2. Urine
3. Gastric juice
4. Feces
5. Lungs

mirabriestensky · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

Correct Answer: 1

Rationale 1: A biotransformation reaction converts drugs from one form to another that can result in increased or decreased activity.
Rationale 2: Biotransformation is not the final step of excretion of a drug from the body.
Rationale 3: Biotransformation does not change the effect of a drug.
Rationale 4: Biotransformation is not the process of absorption.

Global Rationale: A biotransformation reaction converts drugs from one form to another that can result in increased or decreased activity. Biotransformation is the final step in excretion of a drug from the body; does not change the effect of a drug; is not the process of absorption.

Answer to Question 2

Correct Answer: 1, 2, 4, 5

Rationale 1: Because some drugs are excreted into breast milk, nursing mothers should check with their health care providers before taking any drugs or supplements.
Rationale 2: Urine is the major route of excretion for most drugs.
Rationale 3: Gastric juice is incorrect because it is not a route of excretion for drugs.
Rationale 4: Some drugs are excreted into the bile and are ultimately lost from the body in the feces.
Rationale 5: Some drugs are excreted by the lungs through expiration.

Global Rationale: Drugs can be excreted through breast milk, urine, feces, and the lungs. Gastric juice is incorrect because it is not a route of excretion for drugs.