Author Question: In geriatric patients, the percentage of body fat is increased. What are the pharmacologic ... (Read 15 times)

lidoalex

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In geriatric patients, the percentage of body fat is increased. What are the pharmacologic implications of this physiologic change?
 
  1. A lipid-soluble medication will be eliminated more quickly and not work as well.
  2. A lipid-soluble medication will accumulate in fat tissue and its duration of action may be prolonged.
  3. Absorption of lipid-soluble drugs is impaired in older adults.
  4. The bioavailability of the lipid-soluble drug will be increased in older adults.

Question 2

Robert is complaining of poor sleep. Medications that may contribute to sleep problems in the elderly include:
 
  1. Diuretics
  2. Trazodone
  3. Clonazepam
  4. Levodopa



meltdown117

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Answer to Question 1

ANS: 2
RAT: Lipid medications will accumulate in fatty tissues prolonging the half-lives of these drugs.

Answer to Question 2

1



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