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The toxic levels for lithium carbonate are close to the therapeutic levels. Signs of toxicity include fine hand tremor, polyuria, mild thirst, nausea, general discomfort, diarrhea, vomiting, drowsiness, muscular weakness, lack of coordination, ataxia, giddiness, tinnitus, and blurred vision.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.

