Answer to Question 1
Hydrogen ions and bicarbonate are both electrolytes. Acid-base changes will therefore affect concentrations of other electrolytes in both ECF and intracellular fluid (ICF). For example, movement of HCO3- to the plasma requires the exchange of another negatively charged ion so that electroneutrality is maintained. Chloride is the ion that moves in the opposite direction of HCO3-. Changes in potassium, chloride, and sodium may accompany acid-base disorders.
Answer to Question 2
a