Acetoacetyl-CoA reacts with acetyl-CoA to give product A in the ...

[TFauchery]

Acetoacetyl-CoA reacts with acetyl-CoA to give product A in the presence of 3-hydroxy-3-methyl-glutaryl-CoA synthetase. Identify the special feature of this reaction.
 a. It is enantioselective, and only the S enantiomer is formed.
 b. It is enantioselective, and only the R enantiomer is formed.
 c. It produces a non-superposable R enantiomer.
 d. It produces a racemic mixture used for various purposes.

Question 2

State two differences between Claisen and Aldol condensations.

[chem1s3]

Answer to Question 1

a

Answer to Question 2

The two differences between Claisen and Aldol condensations are as follows:
1 . In the case of Claisen condensations, hydroxides cannot be used as a base as they could react with esters, while for Aldol condensations, hydroxides can be used.
2 . In Aldol condensations, no group is lost, but in the case of Claisen condensations, an alkoxide group is lost.

[TFauchery]

Excellent

[juliaf]

TYSM