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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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About 3% of all pregnant women will give birth to twins, which is an increase in rate of nearly 60% since the early 1980s.
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Asthma cases in Americans are about 75% higher today than they were in 1980.