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Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.
Excessive alcohol use costs the country approximately $235 billion every year.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.