Answer to Question 1
Answer: The postsynaptic action of many neurotransmitters is terminated via reuptake of the molecule through the membrane transporter. A drug that blocks such a transporter would be expected to raise the synaptic levels of that neurotransmitter. For a disease or disorder that is thought to result from a low synaptic activity of that transmitter, blockade of the reuptake process would generate a beneficial effect.
Answer to Question 2
Answer: To modulate the internal biochemical activity of the presynaptic cell.
Addictive Drugs
Dopaminergic Drugs Used for Parkinsonism
Selected Targeted Therapies and Miscellaneous Anticancer Drugs
Sample prescriptions of drugs for oral fungal infections.
The branching process in glycogen synthesis
Target lesions