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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.

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Malaria mortality rates are falling. Increased malaria prevention and control measures have greatly improved these rates. Since 2000, malaria mortality rates have fallen globally by 60% among all age groups, and by 65% among children under age 5.

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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.

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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.

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Approximately 500,000 babies are born each year in the United States to teenage mothers.

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