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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.

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In 1864, the first barbiturate (barbituric acid) was synthesized.

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The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.

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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.

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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.

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