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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.

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Acetaminophen (Tylenol) in overdose can seriously damage the liver. It should never be taken by people who use alcohol heavily; it can result in severe liver damage and even a condition requiring a liver transplant.

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During the twentieth century, a variant of the metric system was used in Russia and France in which the base unit of mass was the tonne. Instead of kilograms, this system used millitonnes (mt).

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Giardia is one of the most common intestinal parasites worldwide, and infects up to 20% of the world population, mostly in poorer countries with inadequate sanitation. Infections are most common in children, though chronic Giardia is more common in adults.

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When blood is deoxygenated and flowing back to the heart through the veins, it is dark reddish-blue in color. Blood in the arteries that is oxygenated and flowing out to the body is bright red. Whereas arterial blood comes out in spurts, venous blood flows.

Respiratory Assistive Devices, Patient Using a Peak Flow Meter Respiratory Assistive Devices, Patient Using a Peak Flow Meter
Blood vessels: (A) normal artery, (B) constriction, and (C) arteriosclerosis and atherosclerosis. Blood vessels: (A) normal artery, (B) constriction, and (C) arteriosclerosis and atherosclerosis.
Blood Flow Blood Flow
Co-current flow in a concentric tube heat exchanger Co-current flow in a concentric tube heat exchanger
Control of blood glucose by pancreatic hormones. Control of blood glucose by pancreatic hormones.
Acromegaly caused by a tumor on his pituitary gland Acromegaly caused by a tumor on his pituitary gland
Video: Fermentation pathways

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