How does tolerance occur at the metabolic level?
a) Alcohol dehydrogenase activity increases in the stomach and liver
b) The brain becomes less responsive to the depressant effects of alcohol.
c) Acetaldehyde dehydrogenase activity increases in the kidneys.
d) Alcohol is emptied from the stomach into the small intestine quicker.
Question 2
Why is chewing coca leaves so much less likely to develop into abuse when compared to using pure cocaine?
a) Chewing coca leaves provides for slow absorption of a low dose of cocaine
b) Chewing coca leaves actually does cause abuse and toxicity, but it is culturally accepted.
c) Chewing coca leaves provides for rapid absorption initially, but the dose decreases as cocaine restricts blood flow in the digestive tract.
d) Chewing coca leaves causes the cocaine to travel through the liver before reaching the bloodstream.
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Metabolic Acidosis
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