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In 1844, Charles Goodyear obtained the first patent for a rubber condom.

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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.

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Vaccines prevent between 2.5 and 4 million deaths every year.

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On average, the stomach produces 2 L of hydrochloric acid per day.

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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.

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