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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.