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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.
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In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.