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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
People about to have surgery must tell their health care providers about all supplements they take.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
Patients who cannot swallow may receive nutrition via a parenteral route—usually, a catheter is inserted through the chest into a large vein going into the heart.