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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.