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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Excessive alcohol use costs the country approximately $235 billion every year.
Computer programs are available that crosscheck a new drug's possible trade name with all other trade names currently available. These programs detect dangerous similarities between names and alert the manufacturer of the drug.
There are over 65,000 known species of protozoa. About 10,000 species are parasitic.