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Author Question: A patient comes to a clinician with complaints of depression and anxiety. Given the DSM-5 rule of no ... (Read 27 times) |
By definition, when a medication is administered intravenously, its bioavailability is 100%.
When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.