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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.