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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.
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Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.