Which statements are true regarding congenital heart defects? (Select all that apply.)
◦ Congenital heart disease is the second leading cause of death in infants during the first year of life.
◦ Incidence of heart defects is high in stillbirths, low–birth-weight babies, and spontaneous abortions.
◦ Maternal use of drugs during pregnancy has not been shown to increase congenital heart disease.
◦ The underlying cause of congenital heart disease is known in 30% of cases.
◦ Infants with trisomy 21 have a high incidence of congenital heart disease.