Question 1
Heterochromatin formation in fission yeast involves production of double-stranded RNA by:
◦ sense-antisense RNA pairing.
◦ Drosha cleavage of paired RNA molecules.
◦ an RNA-dependent RNA polymerase.
◦ a DNA-dependent RNA polymerase.
◦ complex RNA secondary folding.
Question 2
Hfq is produced by E. coli and functions:
◦ as an RNA-binding protein to bind many transcripts in the cell to alter translation levels of stress-response proteins.
◦ as an RNA-binding protein to bind many small RNAs, including
oxyS RNA, to enhance its ability to bind to target mRNAs.
◦ as an RNA in RNA-RNA interactions to modulate the activity of Dicer in the RNAi pathway.
◦ as an RNA in RNA-RNA interactions to modulate the function of riboswitches.
◦ as an antisense RNA to target degradation of specific transcripts.
Functions of antibodies.
Glial cells and their functions.
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