During DNA replication, the histone cores in the nucleosomes:
◦ spool along the DNA, maintaining contact.
◦ dissociate from the DNA and then reform after replication.
◦ the H3-H4 tetramers remain associated with the DNA until replication has passed the site, when the full core reforms.
◦ the H2A-H2B dimers remain associated with the DNA until replication has passed the site, when the full core reforms.
◦ only the H1 protein remains associated with the DNA until replication has passed the site, when the full core reforms.