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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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Medication errors are three times higher among children and infants than with adults.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.