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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Vaccines prevent between 2.5 and 4 million deaths every year.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
The most common childhood diseases include croup, chickenpox, ear infections, flu, pneumonia, ringworm, respiratory syncytial virus, scabies, head lice, and asthma.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.


