Let us suppose that someone is successful at producing induced pluripotent stem cells (iPS) for replacement of pancreatic insulin-producing cells for people with type 1 diabetes. Which of the following could still be problems?
I. the possibility that, once introduced into the patient, the iPS cells produce nonpancreatic cells
II. the failure of the iPS cells to take up residence in the pancreas
III. the inability of the iPS cells to respond to appropriate regulatory signals
A) I only
B) II only
C) III only
D) I and II
E) all of them
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