Answer to Question 1
ANS: B
Weight gain is the most common feature and results from the accumulation of adipose tissue in the trunk, facial, and cervical areas. These characteristic patterns of fat deposition have been de-scribed as truncal obesity, moon face, and buffalo hump.
Weight gain, not loss, is the most common feature of Cushing syndrome. Pallor is not associated with Cushing syndrome. The skin of the patient with Cushing syndrome is bronze in color.
Answer to Question 2
ANS: D
Overt DM develops in approximately 20 of individuals with hypercortisolism.
Diabetes develops not renal toxicity, but hyperglycemia and hypertension may occur.