What tests are best to distinguish thrombotic thrombocytopenic ...

[jayhills49]

What tests are best to distinguish thrombotic thrombocytopenic purpura from DIC when a patient has schistocytes?
 
  a. Platelet count and morphology
  b. Bone marrow aspirate and biopsy
  c. Reticulocyte count and haptoglobin
  d. PT and PTT

Question 2

Which of the following is an example of a quantitative platelet disorder related to distribution?
 
  a. Thrombotic cytopenic purpura
  b. Essential thrombocythemia
  c. Splenomegaly
  d. Hemolytic uremic syndrome

[parker125]

Answer to Question 1

ANS: D
The best tests, of those listed, to distinguish thrombotic thrombocytopenic purpura from acute DIC are the PT and PTT. Both will be prolonged in DIC, but not affected in thrombotic thrombocytopenic purpura.

Answer to Question 2

ANS: C
An abnormal distribution of platelets may cause of thrombocytopenia. The spleen sequesters approximately one third of the total platelet mass. When the spleen is enlarged (splenomegaly), most platelets are sequestered in the enlarged spleen, resulting in a lower venous blood count.

[jayhills49]

Thanks for the timely response, appreciate it

[parker125]

Great answer, keep it coming