Which of the following is the most specific laboratory test to ...

[Evvie72]

Which of the following is the most specific laboratory test to diagnose chronic myelogenous leukemia?
 
  a. Increased bone marrow fibrosis and reticulin fibers
  b. Increased EOs and basophils in peripheral blood
  c. 5 Blasts in the bone marrow
  d. Leukocyte alkaline phosphatase

Question 2

All of the following are included in the chronic myeloproliferative disorders except:
 
  a. Acute myeloid leukemia
  b. Chronic myelogenous leukemia
  c. Polycythemia vera
  d. Essential thrombocythemia

[Jevvish]

Answer to Question 1

ANS: D
Of the laboratory tests listed, the leukocyte alkaline phosphatase score is most specific for the diagnosis of chronic myelogenous leukemia (where it is below normal in most cases). None of the other findings are specific for chronic myelogenous leukemia.

Answer to Question 2

ANS: A
Acute myeloid leukemia is not included in the chronic myeloproliferative disorders. All the other conditions listed are part of this classification.