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Author Question: Cellulose acetate is performed on a patient with known homozygous Hb S who has received red cell ... (Read 20 times)

amal

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on: Jun 25, 2018
Cellulose acetate is performed on a patient with known homozygous Hb S who has received red cell transfusions in the past week. What hemoglobins would be expected to be found?
 
  a. Hb S and Hb F
  b. Hb A and Hb F
  c. Hb S, Hb A, and Hb F
  d. Hb S, Hb A, Hb F, and Hb A2

Question 2

What is a point mutation?
 
  a. Mutation of the stop codon
  b. Replacement of one nucleotide in the normal gene with a different nucleotide
  c. Addition of one nucleotide in the normal gene
  d. Deletion of one nucleotide in the normal gene


jointhecircus

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: D
Hb S, Hb A, Hb F, and Hb A2 would be seen. Hb A, which is not present in patients with homozygous Hb S, is from the transfused red cells. Hb F and Hb A2 are normal hemoglobins.

Answer to Question 2

ANS: B
Replacement of one nucleotide in the normal gene with a different nucleotide is a point mutation. This results in a different amino acid and can affect the protein's function.


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