This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: What destroys the red cells in paroxysmal nocturnal hemoglobinuria? a. Macrophages in the bone ... (Read 78 times)

dbose

  • Hero Member
  • *****
  • Posts: 597
on: Jun 25, 2018
What destroys the red cells in paroxysmal nocturnal hemoglobinuria?
 
  a. Macrophages in the bone marrow
  b. Antibodies against red cell membrane antigens
  c. Increased susceptibility to complement
  d. Macrophages in the spleen

Question 2

Which of the following is a typical finding in paroxysmal nocturnal hemoglobinuria?
 
  a. Hemosiderin in urine sediment
  b. Normal levels of decay accelerating factor (CD55)
  c. Hemolysis when blood is alkaline
  d. Elevated white cells and platelets


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

JaynaD87

  • Sr. Member
  • ****
  • Posts: 368
Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: C
Red cells in paroxysmal nocturnal hemoglobinuria are abnormally sensitive to complement, which is activated on their surface and results in premature destruction of the red cells.

Answer to Question 2

ANS: A
Hemosiderin is present and a useful diagnostic tool in paroxysmal nocturnal hemoglobinuria. Levels of CD55 are decreased in paroxysmal nocturnal hemoglobinuria. Hemolysis occurs when blood is acidic, and platelets and white cells are usually decreased so that the patient is pancytopenic.


dbose

  • Member
  • Posts: 597
Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

aruss1303

  • Member
  • Posts: 314
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

Chronic marijuana use can damage the white blood cells and reduce the immune system's ability to respond to disease by as much as 40%. Without a strong immune system, the body is vulnerable to all kinds of degenerative and infectious diseases.

Did you know?

Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.

Did you know?

No drugs are available to relieve parathyroid disease. Parathyroid disease is caused by a parathyroid tumor, and it needs to be removed by surgery.

Did you know?

GI conditions that will keep you out of the U.S. armed services include ulcers, varices, fistulas, esophagitis, gastritis, congenital abnormalities, inflammatory bowel disease, enteritis, colitis, proctitis, duodenal diverticula, malabsorption syndromes, hepatitis, cirrhosis, cysts, abscesses, pancreatitis, polyps, certain hemorrhoids, splenomegaly, hernias, recent abdominal surgery, GI bypass or stomach stapling, and artificial GI openings.

Did you know?

The first monoclonal antibodies were made exclusively from mouse cells. Some are now fully human, which means they are likely to be safer and may be more effective than older monoclonal antibodies.

Micrographs of nerve cells taken with different types of light microscopes. Micrographs of nerve cells taken with different types of light microscopes.
Recognition of conformational epitopes by B cells. Recognition of conformational epitopes by B cells.
cells cells
PV cells have potential for domestic and commercial use PV cells have potential for domestic and commercial use
Totipotent stem cells Totipotent stem cells
Gene gun used to blast gold particles containing pea gene A into cells of white petals Gene gun used to blast gold particles containing pea gene A into cells of white petals
Video: What Are Carbohydrates? Importance of Carbs & High Carb Food

For a complete list of videos, visit our video library