Describe the following, and indicate whether they are typically ...

[s.tung]

Describe the following, and indicate whether they are typically seen in disorders of primary or secondary hemostasis.
 
  a. Petechiae
  b. Purpura
  c. Ecchymoses
  d. Hematomas
 
  What will be an ideal response?

Question 2

How do hematologic disorders contribute to the pathogenesis of thrombocytopenia?
 
  What will be an ideal response?

[leannegxo]

Answer to Question 1

Answer: Petechiae: purple pinpoint hemorrhages beneath the skin; typically seen in disorders of primary hemostasis
Purpura: fused petechiae; typically seen in primary hemostatic disorders mostly isolated from vascular disorders
Ecchymoses: bruises larger than 1 cm that closely resembles hematomas, but on the surface of the skin; typically seen in disorders of primary hemostasis
Hematomas: deeper anatomic bruising often associated with traumatic events, but also with hemorrhagic coagulopathies; typically seen in disorders of secondary hemostasis

Answer to Question 2

Answer: Malignancies contribute to insufficient and/or ineffective thrombopoiesis in the bone marrow. These lead to impaired production and/or function of newly produced platelets.