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Author Question: An apparent pancytopenia is noted in a patient's CBC results. A bone marrow aspirate is performed, ... (Read 33 times)

tth

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on: Jun 25, 2018
An apparent pancytopenia is noted in a patient's CBC results. A bone marrow aspirate is performed, and the M:E results are 2:1. Do these results make sense? Why or why not?
 
  What will be an ideal response?

Question 2

Patient results indicate an RPI of 1.8 and an MCV of 109 fl. Do these results make sense? Why or why not?
 
  What will be an ideal response?


dlook33

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: Yes, these results make sense. The M:E ratio examines the relationship between myeloid and erythroid cells. The pancytopenia describes the overall number of cells present.

Answer to Question 2

Yes, these results make sense. This is the classic picture of a megaloblastic patient. Ineffective erythropoiesis is the result of abnormal division of erythroblastic precursors, and a macrocytic MCV is often the result of an absence of folate and Vitamin B12, which are essential proteins in DNA replication.


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