Following carrier testing, it is determined that both the husband ...

[mckennatimberlake]

Following carrier testing, it is determined that both the husband and wife have sickle-cell trait. Which statement by the wife indicates correct understanding of autosomal recessive inheritance?
 
  1. Because both my husband and I carry the trait but do not have the disease, I don't need to have prenatal testing because my baby will also be a carrier.
  2. Because both my husband and I are both carriers, I don't need to have prenatal testing because all of our children will have the disease.
  3. When I become pregnant, I need to have an amniocentesis or other prenatal test to determine whether my baby is affected with sickle-cell disease.
  4. There is no use undergoing prenatal testing as sickle-cell anemia cannot be diagnosed prenatally.

Question 2

An infant has been diagnosed with a mild heart defect. Surgery to correct the defect will not be performed for at least two years. The nurse teaches the parents that a child with a mild heart defect should:
 
  1. Have a low-grade fever until the defect is repaired.
  2. Maintain normal activity.
  3. Not develop congestive heart failure.
  4. Not be given antipyretics.

[nmyers]

Answer to Question 1

3
Rationale 1: The pregnant woman will require prenatal testing as her child will have a 50-50 chance of being a carrier and a 1 in 4 chance of being affected.
Rationale 2: Each child has a 50 chance of carrying the trait and a 25 chance of having the disorder.
Rationale 3: This statement is accurate.
Rationale 4: This statement is inaccurate because sickle-cell anemia can be diagnosed prenatally.
Global Rationale:

Answer to Question 2

2
Rationale 1: Low-grade fever is not a normal finding in a child with a mild cyanotic heart defect and could be a sign of infective endocarditis.
Rationale 2: A child with a mild cyanotic heart defect should be treated as normally as possible without activity adjustment.
Rationale 3: Any child with a heart defect could develop congestive heart failure.
Rationale 4: Fevers are treated with antipyretics so that dehydration is avoided.
Global

[mckennatimberlake]

Thank you

[nmyers]

No problemo