Author Question: As related to inherited disorders, which statement is descriptive of most cases of hemophilia? a. ... (Read 32 times)

cmoore54 · **on:** Jun 28, 2018

As related to inherited disorders, which statement is descriptive of most cases of hemophilia?

a. Autosomal dominant disorder causing deficiency in a factor involved in the blood-clotting reaction
b. X-linked recessive inherited disorder causing deficiency of platelets and prolonged bleeding
c. X-linked recessive inherited disorder in which a blood-clotting factor is deficient
d. Y-linked recessive inherited disorder in which the red blood cells become moon shaped

Question 2

An acquired hemorrhagic disorder that is characterized by excessive destruction of platelets is:

a. Aplastic anemia.
b. Thalassemia major.
c. Disseminated intravascular coagulation.
d. Idiopathic thrombocytopenic purpura.

leannegxo · **Reply #1 on:** Jun 28, 2018

Answer to Question 1

ANS: C
The inheritance pattern in 80 of all of the cases of hemophilia is X-linked recessive. The two most common forms of the disorder are factor VIII deficiency (hemophilia A or classic hemophilia), and factor IX deficiency (hemophilia B or Christmas disease). The disorder involves coagulation factors, not platelets. The disorder does not involve red cells or the Y chromosome.

Answer to Question 2

ANS: D
Idiopathic thrombocytopenic purpura is an acquired hemorrhagic disorder characterized by an excessive destruction of platelets, discolorations caused by petechiae beneath the skin, and a normal bone marrow. Aplastic anemia refers to a bone marrow failure condition in which the formed elements of the blood are simultaneously depressed. Thalassemia major is a group of blood disorders characterized by deficiency in the production rate of specific hemoglobin globin chains. Disseminated intravascular coagulation is characterized by diffuse fibrin deposition in the microvasculature, consumption of coagulation factors, and endogenous generation of thrombin and plasma.