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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
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The FDA recognizes 118 routes of administration.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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If you could remove all of your skin, it would weigh up to 5 pounds.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.