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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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Acetaminophen (Tylenol) in overdose can seriously damage the liver. It should never be taken by people who use alcohol heavily; it can result in severe liver damage and even a condition requiring a liver transplant.
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Thyroid conditions may make getting pregnant impossible.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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The longest a person has survived after a heart transplant is 24 years.