Answer to Question 1
ANS: B
On the basis of these observations, it is now recommended that the tidal volume for patients with ARDS be initiated at 4 to 6 ml/kg.
Answer to Question 2
ANS: C
Until such tools become available, it seems prudent to prevent hypotension (systolic arterial blood pressure at >90 mm Hg, mean arterial blood pressure at >60 mm Hg), consider augmentation of DO2 in the setting of hyperlactatemia, optimize hemoglobin saturation (>90), and ensure ade-quate organ function (e.g., urine output).