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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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There are more nerve cells in one human brain than there are stars in the Milky Way.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.