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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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Walt Disney helped combat malaria by making an animated film in 1943 called The Winged Scourge. This short film starred the seven dwarfs and taught children that mosquitos transmit malaria, which is a very bad disease. It advocated the killing of mosquitos to stop the disease.
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The horizontal fraction bar was introduced by the Arabs.