Author Question: During a medication management class for nurses, the pharmacist discussing tricyclic ... (Read 18 times)

fox · **on:** Jul 19, 2018

During a medication management class for nurses, the pharmacist discussing tricyclic antidepres-sants asked how these medications affect neurotransmitter activity. The nurse should respond:

1. By decreasing available dopamine.
2. By increasing availability of norepinephrine and serotonin.
3. By making available increased amounts of monoamine oxidase.
4. By increasing the effects of gamma-aminobutyric acid.

Question 2

The nurse was leading a medication management group for clients who were being discharged from the hospital. Which of these statements made by a client taking phenelzine (Nardil) would warrant further instruction?

1. I sometimes forget to wear sunscreen when I go for a walk.
2. I need to restrict the amount of sodium in my diet.
3. I should not use over-the-counter cold medications.
4. I usually order liver and onions when my wife and I eat out.

nanny · **Reply #1 on:** Jul 19, 2018

Answer to Question 1

ANS: 2
Tricyclic antidepressants block neurotransmitter uptake, increasing the amounts of norepinephrine and serotonin available. 1. This is the action of typical antipsychotic medication. 3. This is not the action of tricyclics. 4. Benzodiazepines, not tricyclics, increase the effects of GABA.

Answer to Question 2

ANS: 4
MAOIs require clients to observe a tyramine-free diet to prevent hypertensive crisis. Liver is a food that contains large amounts of tyramine. Options 1, 2, and 3 have no relevance for MAOI therapy.