Author Question: The nursing student is preparing a presentation for the class on the relationship of ligands to ... (Read 52 times)

nenivikky · **on:** Jul 19, 2018

The nursing student is preparing a presentation for the class on the relationship of ligands to receptors. Which explanation should the student include in the presentation?

1. The drug ligand works like a key that fits into a lock, which is the receptor protein in the neuron.
2. The drug ligand is the door that opens into the house, which is the neuron.
3. The receptor protein is like a flame that ignites the stove, which is the drug ligand.
4. The drug ligand works like a comforter, providing a protective cover for the receptor protein.

Question 2

Which condition can contribute to a vulnerability of the blood-brain barrier (BBB)? Select all that apply.

1. Anxiety
2. Infection
3. Radiation
4. Dementia
5. High blood pressure

bigsis44 · **Reply #1 on:** Jul 19, 2018

Answer to Question 1

Answer: 1
Explanation: Like a key (drug ligand molecule) fitting into a lock (receptor protein in the neuron cell), the drug molecule ligand tells the protein receptor in the neuron cell to do something (open the gate). The other images (door into a house, flame on a stove, comforter on a bed) do not convey the interaction of the ligand and receptor that results in specific activity.

Answer to Question 2

Answer: 2, 3, 4, 5
Explanation: High blood pressure can open the BBB. Radiation, infection, and brain injury also can open the BBB. The progression of dementia causes a weakening of the BBB. Anxiety has not been associated with BBB vulnerability.