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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Vaccines prevent between 2.5 and 4 million deaths every year.
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More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.