Answer to Question 1
Correct Answer: 2
Rationale: Alprazolam (Xanax) is a benzodiazepine. This drug, which is a central nervous system (CNS) depressant, will likely lead to the most life-threatening withdrawal symptoms in a patient who has stopped taking it. Withdrawal from heroin is very unpleasant, but it is not life threatening. Withdrawal from cocaine is uncomfortable, but it is not life threatening. There is virtually no withdrawal from marijuana.
Answer to Question 2
Correct Answer: 4
Rationale: With chronic alcohol use, the liver adapts and metabolizes alcohol at a faster rate. More of the substance is required to achieve the same effect. This is a phenomenon known as cross-tolerance. This patient has a tolerance to alcohol, so he will require additional anesthesia for surgery since both drugs are CNS depressants. There is no evidence to support that the nurse anesthetist incorrectly calculated the anesthesia dose. Resistance refers to the immune system and infections, and should not be used interchangeably with tolerance. Paradoxical refers to the opposite response; in this case, the patient would have become very excitable; there is no evidence of this.