Author Question: Which statement is accurate regarding pharmacotherapy in the older adult? 1. Increased body water ... (Read 26 times)

Coya19@aol.com · **on:** Jul 23, 2018

Which statement is accurate regarding pharmacotherapy in the older adult?

1. Increased body water can lead to a higher risk of drug toxicity.
2. Plasma levels are increased, leading to a heightened drug response.
3. Generally, drug doses should be increased due to prolonged drug metabolism.
4. Drug absorption is slower due to increased gastric pH.

Question 2

Which of the following kinds of drugs would be most likely to enter breast milk?

1. Ionized
2. Lipid-soluble
3. Water-soluble
4. Bound to plasma protein

Jevvish · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 4
Rationale: The elderly have an increase in gastric pH, which slows absorption. Plasma levels are lower, causing a diminished drug response. Body water is reduced, leading to a higher risk of drug toxicity. Generally, drug doses are reduced because of prolonged drug metabolism.

Answer to Question 2

Correct Answer: 2
Rationale: As with the placenta, drugs that are ionized, water-soluble, and bound to plasma protein are less likely to enter breast milk.