Aspirin is ionized as it enters the small intestine. Which ...

[luvbio]

Aspirin is ionized as it enters the small intestine. Which statement is accurate regarding the absorption of aspirin in the small intestine?
 
  1. Absorption is decreased.
  2. Absorption is increased.
  3. Ionization has nothing to do with the absorption rate.
  4. Aspirin must travel past the small intestine for absorption to occur.

Question 2

Enzymatic activity that changes a medication into a less active form is an example of
 
  1. pharmacodynamics.
  2. active transport.
  3. pharmacokinetics.
  4. diffusion.

[macybarnes]

Answer to Question 1

Correct Answer: 1
Rationale: The small intestine is a more alkaline environment, which facilitates the absorption of basic drugs. Aspirin is an acidic drug that is ionized in the small intestine, and will have lower absorption rates. Higher rates of absorption occur in the stomach (an acidic environment).

Answer to Question 2

Correct Answer: 3
Rationale: Pharmacokinetics describes how drugs are handled within the body. Pharmacodynamics involves how drugs change the body. Diffusion is the movement of a chemical from an area of higher concentration to an area of lower concentration. Active transport is the movement of a chemical against concentration or gradient. (p. 37)

[luvbio]

Gracias!

[Dominic]

Excellent