What is the goal of pharmacologic therapy in treating Parkinson's disease?
1. Increase the amount of acetylcholine at the presynaptic neurons.
2. Decrease the amount of dopamine available in the substantia nigra.
3. Balance cholinergic and dopaminergic activity in the brain.
4. Block dopamine receptors in both presynaptic and postsynaptic neurons.
Question 2
A patient with Parkinson's disease who has been positively responding to drug treatment suddenly develops a relapse of symptoms. Which explanation by the nurse is appropriate?
1. You have apparently developed resistance to your current medication and will have to change to another drug.
2. This is an atypical response. Unfortunately, there are no other options for drug therapy to treat your disease.
3. This is called the on-off phenomenon.' Your health care provider can change your medication regimen slightly to help diminish this effect.
4. You should keep taking your medication at the current dose. These effects will go away with time.
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