Answer to Question 1
Correct Answer: 2
Rationale 1: This describes biologic response modifiers.
Rationale 2: This describes antimetabolites.
Rationale 3: This describes antibiotic antineoplastics.
Rationale 4: This describes alkylating agents.
Global Rationale: Antimetabolites disrupt the critical cellular pathways of cancer cells which slows growth or kills the cell. Biologic response modifiers use the body's immune system to kill tumor cells. Antibiotic antineoplastics contain bacterial substances that can kill cancer cells. Alkylating agents change the shape of the DNA and prevent division of cancer cells.
Answer to Question 2
Correct Answer: 1,2
Rationale 1: Pemetrexed is a medication that is similar in action to methotrexate.
Rationale 2: Pralatrexate is a medication that is similar in action to methotrexate.
Rationale 3: Idarubicin is an antibiotic antineoplastic. It is not similar to methotrexate.
Rationale 4: Plicamycin is an antibiotic antineoplastic. It is not similar to methotrexate.
Rationale 5: Doxorubicin is an antibiotic antineoplastic. It is not similar to methotrexate.
Global Rationale: Pemetrexed and pralatrexate are both similar in action to methotrexate. Idarubicin, plicamycin, and doxorubicin are antibiotic antineoplastics.
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