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Author Question: A client smokes regularly. She takes theophylline (Theo-Dur and others) daily. What is an effect of ... (Read 59 times)

elizabeth18

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on: Jul 23, 2018
A client smokes regularly. She takes theophylline (Theo-Dur and others) daily. What is an effect of smoking while on theophylline?
 
  a. Decrease in theophylline clearance
  b. Increase in theophylline clearance
  c. Increase in the distribution of theophylline
  d. Decrease in the dose for theophylline

Question 2

Cimetidine (Tagamet) is an enzyme inhibitor for the medication theophylline. Drugs that are enzyme inhibitors:
 
  a. convert drugs to metabolites.
  b. increase metabolism, promoting drug elimination.
  c. decrease metabolism, promoting an increase in plasma drug concentration.
  d. increase drug action.


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ilianabrrr

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Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B
Smoking increases hepatic enzyme activity, increasing the clearance of theophylline (Theo-Dur and others). Smokers may need an increased dose of medication.

Answer to Question 2

ANS: C
An enzyme inhibitor decreases the metabolism of certain drugs.


elizabeth18

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Reply 2 on: Jul 23, 2018
Thanks for the timely response, appreciate it

bblaney

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Reply 3 on: Yesterday
Excellent

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